Oklahoma State University

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Lloyd, Pamela G

Associate Professor

Specialty: Cardiovascular Physiology

Ph.D. (Physiology, University of Missouri, 2000)
Postdoctoral Fellow (Univ. of MO College of Vet. Med, 2000-2003)

Department: Physiological Sciences

Contact Information:
269 McElroy Hall
Stillwater, OK 74078
Office: (405) 744-9019
Fax: (405) 744-8263
Send eMail

Fields of Interest:

Angiogenesis, Arteriogenesis, Diabetes, Metabolic Syndrome, Peripheral Arterial Disease, Coronary Artery Disease

Current Research Focus:

Research in our lab focuses on identifying signaling pathways that control blood vessel growth. Modulation of blood vessel growth could potentially be used to treat a wide variety of diseases, including ischemic cardiovascular disease and cancer. However, greater understanding of the mechanisms controlling blood vessel growth is needed before such treatments can achieve their full potential. Current research in our lab is focused on characterizing the signaling pathways that regulate expression of placenta growth factor (PLGF), a protein that stimulates blood vessel growth.

Current Lab Members:

Jennifer H. Shaw, Ph.D. - Research Associate
Rohan Varshney, Ph.D. - Postdoctoral Fellow
Nabil Rashdan, M.S. - Ph.D. Student
Asitha Silva, M.S. - Ph.D. Student
Jamie Smith - Student Assistant

Professional Experience:
Assistant Professor (2006-), Physiological Sciences, Center for Veterinary Health Sciences, Oklahoma State University (Stillwater, OK)
Assistant Research Professor (2004-2006), Cellular & Integrative Physiology, Indiana University School of Medicine (Indianapolis, IN)
Research Assistant Professor (2003-2004), Medical Pharmacology and Physiology, University of Missouri (Columbia, MO)

Professional Affiliations:
American Physiological Society
American Heart Association
Microcirculatory Society

Selected Publications:
1.      Shaw J, Xiang L, Shah A, Yin W, and Lloyd PG. Placenta growth factor expression is regulated by hydrogen peroxide in vascular smooth muscle cells. American Journal of Physiology: Cell Physiology 300 (2): C349-355, 2011.
2.      Lloyd PG and Hardin C. Caveolae and cancer: two sides of the same coin? American Journal of Physiology: Cell Physiology 300 (2): C232-234, 2011.
3.      Yang HT, Prior BM, Lloyd PG, Taylor JC, Laughlin MH, and Terjung RL. Training-induced vascular adaptations to ischemic muscle. Journal of Physiology and Pharmacology 59 (Suppl 7): 57-70, 2008.
4.      Lloyd PG, Sheehy AS, Edwards JM, Mokelke EA, Vuchetich JP, and Sturek M. Leukemia inhibitory factor is upregulated in stented coronary arteries of Ossabaw swine. Coronary Artery Disease 19(4): 217-226, 2008.
5.      Edwards JM, Long XL, Alloosh MA, Dick GM, Lloyd PG, Mokelke EA, and Sturek M. Adenosine A1 receptors in neointimal hyperplasia and in-stent stenosis in Ossabaw miniature swine model of the metabolic syndrome. Coronary Artery Disease 19(1): 27-31, 2008.
6.      Sturek M, Alloosh M, Wenzel J, Byrd JP, Edwards JM, Lloyd PG, Tune JD, March KL, Miller MA, Mokelke EA, and Brisbin IL Jr. Ossabaw Island miniature swine: cardiometabolic syndrome assessment. In Swine in the Laboratory:  Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition. M.M. Swindle (Ed.). Boca Raton: CRC Press, 2007.
7.      Mattern HM, Lloyd PG, Sturek M, and Hardin CD. Gender and genetic differences in bladder smooth muscle PPAR mRNA in a porcine model of the metabolic syndrome. Molecular & Cellular Biochemistry 302: 43-49, 2007.

Courses Taught:
VBSC 5010, Professional Skills for Biomedical Scientists
VBSC 5013, Cell and Molecular Biology
VMED 7114, Veterinary Physiology I (cardiovascular physiology section)